Substituted 6-phenyldihydro-3(2h)-pyridazinones, a process...

C - Chemistry – Metallurgy – 07 – D

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C07D 237/04 (2006.01) A61K 31/495 (2006.01) C07D 401/10 (2006.01) C07D 403/00 (2006.01) C07D 403/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 1316535

ABSTRACT The present invention relates to novel 6- phenyldihydro 3-(2H)-pyridazinones corresponding to the formula Image (I) in which R1 denotes a nitro or a cyano group, R2 denotes a hydrogen atom or a methyl group and R3 stands for an ethoxycarbonyl or an acetyl group, and the physiologically acceptable salts thereof. These compounds are readily prepared in a form suitable for oral administration and are distinguished by a high positive inotropic action and have only a slight effect on blood pressure and cardiac frequency. A process for their preparation and pharmaceutical preparations containing these compounds are also described.

586764

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