Substituted 7-azabicyclo[2.2.1]heptyl derivatives useful for...

C - Chemistry – Metallurgy – 07 – D

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C07D 487/08 (2006.01) A61K 31/407 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2638573

The present invention relates to a group of substituted-7-azabicyclo--[2.2.1]heptyl derivatives with biological activity. The present invention also relates to synthetic methods for producing said substituted-7-azabicyclo--[2 2.1]heptyl derivatives. The present invention also relates to certain intermediates for producing such substituted-7-azabicyclo-[2 2.1]heptyl derivatives, as well as a synthetic method for producing such intermediates. The present invention also relates to pharmaceutical compositions comprising such substituted-7-azabicyclo-[2.2.1]heptyl deriva-tives, as well as their use as medicaments for the treatment of diseases mediated by a Nicotinic Acetylcholine Receptor or a receptor being a member of the Neurotransmitter--gated Ion Channel Superfamily, such as pain, Alzheimer's disease, Parkinson's disease, schizophrenia, epilepsy and nicotine addiction.

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