Substituted 8-arylquinoline phosphodiesterase-4 inhibitors

Details Substituted 8-arylquinoline phosphodiesterase-4 inhibitors Substituted 8-arylquinoline phosphodiesterase-4 inhibitors

C - Chemistry, Metallurgy

07

D

C07D 413/10 (2006.01) A61K 31/4709 (2006.01)

Patent

CA 2431549

Novel sulfuric acid, methanesulfonic acid, p-toluenesulfonic acid, 2- naphthalenesulfonic acid, hydrochloride acid, or benzenesulfonic acid salts of substituted 8-arylquinolines, wherein the aryl group at the 8-position contains a substituent substituted-alkenyl group, are PDE4 inhibitors.

L'invention concerne des sels d'acide sulfurique, d'acide méthanesulfonique, d'acide p-toluènesulfonique, d'acide 2-naphthalènesulfonique, d'acide chlorhydrique ou d'acide benzènesulfonique d'arylquinolines à substitution en 8, où le groupe aryle en position 8 contient un groupe substituant à substitution alcényle. Les substances considérées sont des inhibiteurs de phospodiestérase-4.

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