Substituted 9-amino-tetrahydroacridines and related...

Details Substituted 9-amino-tetrahydroacridines and related... Substituted 9-amino-tetrahydroacridines and related...

C - Chemistry, Metallurgy

07

D

167/227, 260/514

C07D 219/10 (2006.01) A61K 31/435 (2006.01) C07D 219/04 (2006.01) C07D 219/06 (2006.01) C07D 221/16 (2006.01)

Patent

CA 1318675

ABSTRACT Substituted 9-amino-tetrahydroacridines and related com- pounds, a process for their preparation and their use as medicaments There are disclosed compounds having the formula Image wherein n is 1-4; X is alkyl of 3-18 carbon atoms, cycloalkyl of 3-7 carbon atoms or cycloalkylloweralkyl; R is hydrogen, loweralkyl or loweralkylcarbonyl; R1 is hydrogen, loweralkyl, loweralkylcarbonyl, aryl, diloweralkylaminoloweralkyl, arylloweralkyl, diarylloweralkyl, oxygen-bridged arylloweralkyl or oxygen-bridged diarylloweralkyl; stereo isomers thereof and pharmaceutically acceptable acid addition salts thereof, which are useful for enhancing memory, methods for synthesizing them, and pharmaceutical compositions comprising an effective memory enhancing amount of such a compound.

561561

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