C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 323/41 (2006.01) A61K 31/165 (2006.01) A61K 31/33 (2006.01) C07C 317/32 (2006.01) C07C 317/44 (2006.01) C07C 323/60 (2006.01) C07D 213/70 (2006.01) C07D 215/36 (2006.01) C07D 233/28 (2006.01) C07D 233/84 (2006.01) C07D 239/38 (2006.01) C07D 263/46 (2006.01) C07D 277/36 (2006.01) C07D 307/91 (2006.01) C07D 333/18 (2006.01) C07D 333/62 (2006.01)
Patent
CA 2105617
ABSTRACT OF THE DISCLOSURE There are provided substituted acetamide derivatives represented by general formula (I): Image (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, n and Z are defined in the specification. The substituted acetamide derivatives strongly inhibit acyl- coenzyme A cholesterol acyltransferase (ACTA) and are expected to be effective for the treatment and prevention of hypercholesterolemia, hyperlipemia and arteriosclerosis.
Hattori Hiromi
Iwasawa Yoshikazu
Nagata Yasufumi
Sawasaki Yoshio
Shimizu Akiko
Banyu Pharmaceutical Co. Ltd.
Ridout & Maybee Llp
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