Substituted acetamide derivatives, process for their...

Details Substituted acetamide derivatives, process for their... Substituted acetamide derivatives, process for their...

C - Chemistry, Metallurgy

07

D

167/228, 167/233

C07D 295/155 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C08B 37/16 (2006.01)

Patent

CA 2016240

ABSTRACT OF THE DISCLOSURE A substituted acetamide derivative of general formula (I): Image ( I ) [in which Y represents a piperidino group, 1-pyrrolidinyl group or 3-hydroxy-1-pyrrolidinyl group, and Z represents a group selected from the group consisting of (a) to (e): (a) a cyano group, (b) Image (c) Image (d) Image (e) Image its salts, its cyclodextrin inclusion compounds and antiulcer drugs comprising them as their active ingredient are disclosed. Compounds (I) have excellent antiulcer actions and are highly safe, thus the antiulcer drugs containing the compounds are useful as a preventive and curative medicine against acute and chronic gastric ulcers, duodenal ulcers and gastric hyperacidities.

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