Substituted acetophenones and process therefor

C - Chemistry – Metallurgy – 07 – C

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C07C 69/00 (2006.01) C07C 45/74 (2006.01) C07C 49/84 (2006.01) C07D 235/06 (2006.01) C07D 307/68 (2006.01) C07F 9/12 (2006.01) C07H 17/07 (2006.01)

Patent

CA 1137082

ABSTRACT A process for the preparation of novel substituted aceto- phenone derivatives of the general formula Image (I) wherein R1 represents a hydroxyl radical, a phos- phonooxy radical, an aminoglycosyloxy radical which may be acylated, a benzyloxycarbonyloxy radical, a substituted or unsubstituted arycarbonyloxy radical, a trialkylammonioacyloxy radical or a furoyloxy radical; R2 and R3 represent each a lower alkoxy radical; and R4 represents a benzimidazolyl radical, a furyl or thienyl radical which may be substituted by a lower alkyl radical, or a phenyl radical which is substituted by a lower alkyl radical, a lower alkoxy radical, an alkyl- thio radical, an alkylenedioxy radical or an acyloxy radical, with the proviso that when R1 represents a hydroxyl radical, R4 represents a benzimidazolyl radical or phenyl radical which is substituted by an acyloxy radical. These compounds are useful as ingredients for antiviral agents.

351137

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