C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
260/228, 260/461
C07C 69/00 (2006.01) C07C 45/74 (2006.01) C07C 49/84 (2006.01) C07D 235/06 (2006.01) C07D 307/68 (2006.01) C07F 9/12 (2006.01) C07H 17/07 (2006.01)
Patent
CA 1137082
ABSTRACT A process for the preparation of novel substituted aceto- phenone derivatives of the general formula Image (I) wherein R1 represents a hydroxyl radical, a phos- phonooxy radical, an aminoglycosyloxy radical which may be acylated, a benzyloxycarbonyloxy radical, a substituted or unsubstituted arycarbonyloxy radical, a trialkylammonioacyloxy radical or a furoyloxy radical; R2 and R3 represent each a lower alkoxy radical; and R4 represents a benzimidazolyl radical, a furyl or thienyl radical which may be substituted by a lower alkyl radical, or a phenyl radical which is substituted by a lower alkyl radical, a lower alkoxy radical, an alkyl- thio radical, an alkylenedioxy radical or an acyloxy radical, with the proviso that when R1 represents a hydroxyl radical, R4 represents a benzimidazolyl radical or phenyl radical which is substituted by an acyloxy radical. These compounds are useful as ingredients for antiviral agents.
351137
Ishitsuka Hideo
Shinma Nobuo
Suhara Yasuji
Umeda Isao
Gowling Lafleur Henderson Llp
Hoffmann-La Roche Limited
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