Substituted alkylamine derivatives and methods of use

Details Substituted alkylamine derivatives and methods of use Substituted alkylamine derivatives and methods of use

C - Chemistry, Metallurgy

07

D

C07D 413/14 (2006.01) A61K 31/395 (2006.01) A61P 35/00 (2006.01) C07D 213/82 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/04 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2434277

Selected heterocyclic compoundsare effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds of Formula II' (shown below), analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compousitions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes. (see above formula)

L'invention a pour objet des composés hétérocycliques sélectionnés qui sont efficaces dans la prophylaxie et le traitement de maladies telles que les maladies induites par angiogenèse. Cette invention a trait à de nouveaux composés, analogues, promédicaments et dérivés de ces derniers pharmaceutiquement acceptables, à des compositions et à des méthodes pharmaceutiques utilisées dans la prophylaxie et le traitement de maladies et autres affections ou atteintes comme le cancer ou maladies similaires. L'invention porte également sur des procédés de fabrication de ces composés ainsi que sur des produits intermédiaires utiles dans de tels procédés.

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