C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/14 (2006.01) A61K 31/4433 (2006.01) A61K 31/4439 (2006.01) A61K 31/444 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 407/14 (2006.01) C07D 413/14 (2006.01)
Patent
CA 2492045
Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
L'invention concerne des amines sélectionnées efficaces en matière de prophylaxie et traitement de maladies telles que des maladies médiées par l'angiogenèse. Cette invention concerne également de nouveaux composés, analogues, promédicaments et sels pharmaceutiquement acceptables de ces derniers, des compositions pharmaceutiques ainsi que des méthodes de prophylaxie et de traitement de certaines maladies ou pathologies, notamment du cancer et analogues. Ladite invention concerne également des procédés de production desdits composés ainsi que des intermédiaires utiles à la mise en oeuvre de ces procédés.
Askew Benny C. Jr.
Booker Shon
Chen Guoqing
Dipietro Lucian V.
Elbaum Daniel
Amgen Inc.
Gowling Lafleur Henderson Llp
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