Substituted amino acids, their use and production and...

Details Substituted amino acids, their use and production and... Substituted amino acids, their use and production and...

C - Chemistry, Metallurgy

07

K

260/514.2, 260/5

C07K 5/02 (2006.01) A01N 37/12 (2006.01) C07C 233/46 (2006.01)

Patent

CA 1153387

ABSTRACT Acylbiphenylylaminoalkanoic acids of the general formula I (I), Image in which R1 signifies an aliphatic or alicyclic hydrocarbon radical or an optionally substituted phenyl group, A signi- fies an optionally substituted and/or hydrogenated biphenylyl radical and n signifies a positive whole number from 3 to 5, as well as their salts of inorganic or organic bases exert on warm-blooded animals a protective action on the stomach and liver, and in addition they bring about an in- crease in the secretion of the pancreas and liver. In addition, they cause an inhibition of the formation of glucose from lactate and pyruvate in the liver. They are suitable for the treatment and prophylaxis of diseases which are due to dis- orders of the stomach or intestine or to reduced performances by the pancreas, bile and/or liver. Processes for the pro- duction of the compounds and corresponding pharmaceutical products are given.

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