C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 237/20 (2006.01) A61K 31/16 (2006.01) A61P 25/28 (2006.01)
Patent
CA 2450557
The invention provides compounds of formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.
L'invention concerne des composés représentés par la formule (I) utilisés pour traiter la maladie d'Alzheimer et d'autres maladies similaires. Ces composés comprennent des inhibiteurs de l'enzyme bêta-secretase utilisés pour traiter la maladie d'Alzheimer et d'autres maladies caractérisées par le dépôt du peptide bêta A chez un mammifère. Lesdits composés sont utilisés dans des compositions pharmaceutiques et dans des méthodes de traitement permettant de réduire la formation du peptide bêta A.
Maillard Michel
Tucker John Alan
Elan Pharmaceuticals Inc.
Osler Hoskin & Harcourt Llp
Pharmacia & Upjohn Company
Pharmacia & Upjohn Company Llc
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