C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 261/04 (2006.01) C07D 413/10 (2006.01) C07D 413/12 (2006.01) C07D 417/10 (2006.01) C07D 521/00 (2006.01)
Patent
CA 2315735
The present invention provides novel substituted aminophenyl isoxazoline derivatives of formula (I), wherein R1 is H, alkyl, cycloalkyl, alkoxy, amino, or alkylamino; X and Y are the same and different and are H, F, or CH3; W is O, or S; Q is a 4-, 5-, 6-, 7-, or 9-membered heterocyclic moiety containing one or more nitrogen, sulfur and/or oxygen. The compounds of the invention are useful as antimicrobial agents for preventing and treating infectious diseases.
La présente invention porte sur de nouveaux dérivés d'isoxazoline aminophényle substitués de la formule (I) dans laquelle R¿1? représente H, alkyle, cycloalkyle, amino ou alkylamino; X et Y sont identiques et différents et représentent H, F ou CH¿3?; W représente O, S; Q représente une fraction hétérocyclique à 4, 5, 6, 7 ou 9 éléments et contenant au moins un azote, soufre et/ou oxygène. Les composés de cette invention sont utiles comme agents antimicrobiens dans la prévention et le traitement de maladies infectieuses.
Barbachyn Michael R.
Cleek Gary J.
Morris Joel
Thomas Richard C.
Wishka Donn G.
Macrae & Co.
Pharmacia & Upjohn Company
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