C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) A61P 3/00 (2006.01) C07D 239/42 (2006.01) C07D 401/12 (2006.01)
Patent
CA 2676222
Certain novel substituted aminopyrimidines are ligands of the human cholecystokinin receptor and, in particular, are selective ligands of the human cholecystokinin-1 receptor (CCK-1R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of CCK-1R, such as obesity, and diabetes.
L'invention concerne certaines nouvelles aminopyrimidines substituées qui sont des ligands du récepteur humain de la cholécystokinine et, en particulier, qui sont des ligands sélectifs du récepteur humain de la cholécystokinine-1 (CCK-1R). Elles s'utilisent donc pour le traitement, le contrôle ou la prévention de maladies et de troubles sensibles à la modulation de CCK-1R, tels que l'obésité et le diabète.
Edmondson Scott
Kaelin Daniel E.
Sweis Randy
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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