Substituted aminothiazole derivatives with anti-hcv activity

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 417/04 (2006.01) A61K 31/426 (2006.01) A61K 31/4439 (2006.01) A61P 31/14 (2006.01) C07D 277/44 (2006.01) C07D 277/56 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2645072

The invention provides amino-substituted aminothiazole compounds of formula (I) in which A is a group of the formula and the variables R and R1 to R7 are described herein. These compounds are useful as inhibitors of viral replication. Compositions containing such compounds, and methods of treating viral infections with these compounds, as well as to processes and intermediates useful for preparing such compounds are also provided by the invention.

La présente invention concerne des composés aminothiazole amino-substitués de formule I (formule I) dans laquelle A est un groupe de la formule : et les variables R et R1 à R7 sont décrites ici. Ces composés sont utiles en tant qu'inhibiteurs de réplication virale. La présente invention concerne également des compositions contenant de tels composés et des procédés de traitement d'infections virales par ces composés, ainsi que des procédés et des intermédiaires utiles pour la préparation de tels composés.

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