Substituted androsta-1,4-diene-3,17-diones and process for...

Details Substituted androsta-1,4-diene-3,17-diones and process for... Substituted androsta-1,4-diene-3,17-diones and process for...

C - Chemistry, Metallurgy

07

J

167/198, 260/39

C07J 1/00 (2006.01) A61K 31/565 (2006.01)

Patent

CA 1277656

ABSTRACT SUBSTITUTED ANDROSTA-1,4-DIENE-3,17-DIONES AND PROCESS FOR THEIR PREPARATION The invention relates to 6-alkylidenandrosta-1,4-diene- -3,17-dione derivatives, having the following general formula Image wherein each of R and R2, independently, is hydrogen or C1-C6 alkyl and R1 is hydrogen, halogen or C1-C6 alkyl, which are useful in therapy, in particular in the treatment of hormone-dependent cancers.

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