Substituted anthra¬1,9-cd|pyrazol-6-(2h)-ones

C - Chemistry – Metallurgy – 07 – D

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C07D 231/54 (2006.01) C07D 403/02 (2006.01) C07D 403/06 (2006.01) C07D 413/02 (2006.01) C07D 413/06 (2006.01)

Patent

CA 1256431

ABSTRACT Substituted anthra[1,9-cd]pyrazol-6(2H)-ones having antimicrobial activity, methods for their preparation and use, and pharmaceutical compositions containing them are disclosed. The novel compounds have the general formula: Image wherein R is H or C1-6alkyl, and Y and Z are aa defined in the disclosure and claims. The novel compounds are prepared by reacting an amine of general formula: HNRY with a compound of general formula: Image

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