Substituted aromatic sulfonamides as antiglaucoma agents

C - Chemistry – Metallurgy – 07 – D

Patent

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167/208, 260/305

C07D 495/04 (2006.01) A61K 31/38 (2006.01) A61K 31/395 (2006.01) C07D 495/20 (2006.01)

Patent

CA 2040312

Thieno[2,3-b]thiopyran-2-sulfonamides and ring homologs with a hydrophilic substituted-alkyl group adjacent to the thiopyran sulfur are carbonic anhydrase inhibitors topically effective in lowering intraocular pressure.

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