Substituted aryl and heteroaryl derivatives as modulators of...

Details Substituted aryl and heteroaryl derivatives as modulators of... Substituted aryl and heteroaryl derivatives as modulators of...

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/506 (2006.01) A61P 3/10 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2568451

The present invention relates to certain substituted aryl and heteroaryl derivative of Formula (I) that are modulators of metabolism, especially of the activity of a GPCR, referred to herein as RUP3. Accordingly, compounds of the present invention are useful in the treatment of metabolic-related disorders and complications thereof, such as, diabetes and obesity.

Certains dérivés d'aryle et d'hétéroaryle substitués de formule (I) sont des modulateurs du métabolisme. Les composés de cette invention sont utilisés dans le traitement de troubles associés au métabolisme et de leurs complications, notamment du diabète et de l'obésité.

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