Substituted (arylalkoxybenzyl) amino-propanamide derivatives...

Details Substituted (arylalkoxybenzyl) amino-propanamide derivatives... Substituted (arylalkoxybenzyl) amino-propanamide derivatives...

C - Chemistry, Metallurgy

07

C

C07C 237/06 (2006.01) A61K 31/16 (2006.01) C07C 237/00 (2006.01)

Patent

CA 2135783

The invention provides new compounds of formula (I) wherein, subject to a proviso, n is zero or an integer of 1 to 3: each of R and R1, which may be the same or different, is hydrogen, halogen, trifluoromethyl or C1-C4 alkoxy; R2 is hydrogen or C1-C4 alkyl optionally substituted by hydroxy: each of R3 and R4 independently is hydrogen or C1-C4 alkyl; or a pharmaceutically acceptable salt thereof; and of formula (IA), (see formula IA) wherein R5 is hydrogen, halogen, trifluoromethyl or C1-C4 alkoxy, or a pharmaceutically acceptable salt thereof, which are active on the central nervous system (CNS) and can be used is therapy as anti- epileptics, anti-Parkinson, neuroprotective, antidepressant, anti-spastic and hypnotic agents.

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