Substituted arylcyclopentenes as prostaglandin ep2 agonists

Details Substituted arylcyclopentenes as prostaglandin ep2 agonists Substituted arylcyclopentenes as prostaglandin ep2 agonists

C - Chemistry, Metallurgy

07

D

C07D 333/38 (2006.01) A61K 31/381 (2006.01) A61P 17/14 (2006.01) A61P 27/06 (2006.01)

Patent

CA 2722456

Compounds comprising formula (I) or a pharmaceutically acceptable salt or a prodrug thereof, are disclosed, wherein Y, A, and B are as described. Methods, compositions, and medicaments for the treatment of glaucoma, ocula hypertension and inflammatory bowel disease, and for the stimulation of hair growth are also disclosed.

L'invention porte sur des composés comprenant la formule (I) ou un sel pharmaceutiquement acceptable ou un promédicament de ceux-ci, formule dans laquelle Y, A et B sont tels que décrits. L'invention porte également sur des procédés, des compositions et des médicaments pour le traitement d'un glaucome, d'une hypertension oculaire et d'une affection intestinale inflammatoire, et pour la stimulation de la pousse des cheveux.

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