Substituted aza- and diazacycloheptane and cyclooctane...

Details Substituted aza- and diazacycloheptane and cyclooctane... Substituted aza- and diazacycloheptane and cyclooctane...

C - Chemistry, Metallurgy

07

D

C07D 403/14 (2006.01) A61K 31/41 (2006.01) A61K 31/505 (2006.01) A61K 31/55 (2006.01) C07D 223/04 (2006.01) C07D 243/08 (2006.01) C07D 245/02 (2006.01) C07D 401/14 (2006.01) C07D 403/02 (2006.01) C07D 403/04 (2006.01) C07D 403/12 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2241787

The present invention concerns aza- and diazacycloheptane and cyclooctane compounds from the following formula (I) Ar1-A-B-Ar2 wherein Ar1, A, B, and Ar2 have the meanings given in the description. The compounds according to the invention possess a high affinity with the dopamine-D3-receptors and can therefore be used for the treatment of illness, which react to dopamine-D3-ligands.

L'invention concerne des composés aza- et diazacycloheptane et -cyclo-octane de formule (I) Ar<1>-A-B-Ar<2>, dans laquelle Ar<1>, A, B et Ar<2> ont la signification donnée dans la description. Les composés selon l'invention présentent une affinité élevée pour le récepteur de la dopamine D3 et sont donc utiles pour le traitement de maladies sensibles aux ligands de la dopamine D3.

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