C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 495/04 (2006.01) A61K 31/55 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2565683
The present invention generally relates to a series of compounds, to pharmaceutical compositions containing the compounds, and to use of the compounds and compositions as therapeutic agents. More specifically, compounds of the present invention are hexahydroazepinoindole and octahydroazepinoindole compounds. These compounds are serotonin receptor (5-HT) ligands and are useful for treating diseases, disorders, and conditions wherein modulation of the activity of serotonin receptors (5-HT) is desired (e.g. anxiety, depression and obesity).
La présente invention concerne d'une manière générale une série de composés, des compositions pharmaceutiques contenant ces composés et l'utilisation de ces composés et de ces compositions comme agents thérapeutiques. Plus spécifiquement, les composés de cette invention sont des composés hexahydroazepinoindole et octahydroazepinoindole. Ces composés sont des ligands des récepteurs de la sérotonine (5-HT) et conviennent pour traiter des maladies, des troubles et des états dans lesquels la modulation de l'activité des récepteurs de la sérotonine (5-HT) est recherchée (par exemple l'anxiété, la dépression et l'obésité).
Bennani Youssef L.
Bom David C.
Robarge Michael J.
Tumey Lawrence N.
Varga Norbert
Athersys Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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