Substituted azetidinones as anti-inflammatory...

C - Chemistry – Metallurgy – 07 – D

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C07D 205/08 (2006.01) C07D 401/08 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 521/00 (2006.01)

Patent

CA 1337990

New substituted azetidinones of Formula I are found as potent elastase inhibitors and thereby useful anti- inflammatory and anti-degenerative agents Image (I) The active substituted azetidinones can be used to provide pharmaceutical compositions as protease inhibitors useful for controlling tissue damage and various inflammatory or degenerative conditions mediated by proteases particularly elastase.

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