C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 491/056 (2006.01) A61K 31/4741 (2006.01) A61K 31/4745 (2006.01) A61P 3/00 (2006.01) A61P 3/08 (2006.01) C07D 498/04 (2006.01)
Patent
CA 2757084
The present invention is directed to substituted azoanthracene derivatives or pharmaceutically acceptable salts thereof that modulate the human GLP-1 receptor and that may be useful in the treatment of diseases, disorders, or conditions in which modulation of the human GLP-1 receptor is beneficial, such as diabetes mellitus type 2. The invention is also directed to pharmaceutical compositions comprising these compounds and to the use of these compounds and compositions in the treatment of such diseases, disorders, or conditions in which modulation of the human GLP-1 receptor is beneficial.
La présente invention porte sur des dérivés d'azoanthracène substitués ou sur leurs sels pharmaceutiquement acceptables, qui modulent le récepteur au GLP-1 humain et qui peuvent être utiles dans le traitement de maladies, troubles ou états dans lesquels une modulation du récepteur au GLP-1 humain est utile, tels que le diabète sucré de type 2. L'invention porte également sur des compositions pharmaceutiques comprenant ces composés et sur l'utilisation de ces composés et de ces compositions dans le traitement de telles maladies, troubles ou états dans lesquels la modulation du récepteur au GLP-1 humain est utile.
Andrews Robert Carl
Behme Christopher
Bondlela Muralidhar
Christen Daniel P.
Davis Stephen Thomas
Smart & Biggar
Transtech Pharma Inc.
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