C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61K 31/50 (2006.01) A61K 31/505 (2006.01) A61K 31/695 (2006.01) C07D 233/70 (2006.01) C07D 249/12 (2006.01) C07D 401/04 (2006.01) C07D 401/10 (2006.01) C07D 401/12 (2006.01) C07D 403/00 (2006.01) C07D 403/12 (2006.01) C07F 7/10 (2006.01) C07F 7/18 (2006.01)
Patent
CA 2155830
The use for the manufacture of a medicament for treating Helicobacter-related diseases of a compound of formula (I), a pharmaceutically acceptable acid addition salt or stereochemically isomeric form thereof, wherein X and Y each independently are CH or N; R1, R2 and R3 each independently are hydrogen or C1-4alkyl; R4 and R5 each independently are hydrogen, halo, C1-4alkyl, C1- 4alkyloxy hydroxy, trifluoromethyl, trifluoromethyloxy or difluoromethyloxy; Z is C = O or CHOH; and Ar is phenyl optionally substituted with up to three substituents selected from hydroxy, C1-4alkyl, C1-4alkyloxy, halo, trifluoromethyl, triC1-4alkylsilyloxy, nitro, amino and cyano or pyridinyl substituted with hydroxy or C1-4alkyloxy; and (n) is a radical of formula (a-1), (a-2), (a-3), (a-4), (a-5), (a-6), or (a-7).
Heeres Jan
Mostmans Joseph Hector
Odds Frank Christopher
Stokbroekx Raymond Antoine
Van Der Aa Marcel Josef Maria
Gowling Lafleur Henderson Llp
Janssen Pharmaceutica Naamloze Vennootschap
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