Substituted benzene compounds as antiproliferative and...

Details Substituted benzene compounds as antiproliferative and... Substituted benzene compounds as antiproliferative and...

C - Chemistry, Metallurgy

07

C

C07C 311/21 (2006.01) A61K 31/18 (2006.01)

Patent

CA 2301842

The invention provides compounds, compositions and methods relating to novel electrophilic aromatic derivatives and their use as pharmacologically active agents. The compositions find particular use as pharmacological agents in the treatment of disease states, particularly cancer, psoriasis, vascular restenosis, infections, atherosclerosis and hypercholesterolemia, or as lead compounds for the development of such agents. The compositions include compounds of general Formula (I).

L'invention porte sur des composés, compositions et procédés relatifs à de nouveaux dérivés aromatiques électrophiles et leur utilisation comme agents pharmacologiques actifs pouvant traiter des états morbides tels qu'en particulier le cancer, le psoriasis, les resténoses vasculaires, les infections, l'athérosclérose ou l'hypercholestérolémie, ou sur leurs précurseurs. Lesdites compositions renferment des composés de formule générale (I).

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