Substituted benzimidazoles and benzothidiazoles

C - Chemistry – Metallurgy – 07 – D

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167/223, 167/237

C07D 235/18 (2006.01) A61K 31/495 (2006.01) C07D 285/14 (2006.01) C07D 417/10 (2006.01)

Patent

CA 1317958

61109-7672 Abstract A compound selected from the group consisting of those of the formula: Image (I) Image (II) wherein X is hydrogen, fluoro, chloro, bromo or m-trifluoromethyl and R is alkanoyl (C1-C3), carboalkoxy (C2-C4), m-trifluoromethyl- phenyl or 2-benzoxazolyl and the pharmacologically acceptable acid-addition salts thereof. These compounds are highly active as anti-asthmatic and anti-allergic agents.

583593

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