Substituted benzoic acid alkylene bridged piperidyl amides

Details Substituted benzoic acid alkylene bridged piperidyl amides Substituted benzoic acid alkylene bridged piperidyl amides

C - Chemistry, Metallurgy

07

D

167/231, 260/272

C07D 453/02 (2006.01) A61K 31/44 (2006.01) A61K 31/46 (2006.01) C07D 451/12 (2006.01)

Patent

CA 1267898

Abstract: Compounds are described of formula I A-CO-B-D I wherein A is a group of formula III Image III wherein R4 to R7 independently are hydrogen, amino, nitro, (C1-4)alkylamino, di(C1-4)alkylamino, halogen, (C1-4)alkoxy, (C1-4)alkyl, (C1-4)- alkanoylamino or pyrrolyl, with the proviso that at least one of R4 and R5 is other than hydrogen, B is -NH- and D is a group of the formula V Image V They exhibit seratonin M receptor antagonist activity.

580288

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