Substituted benzopyran analogs for the treatment of...

Details Substituted benzopyran analogs for the treatment of... Substituted benzopyran analogs for the treatment of...

C - Chemistry, Metallurgy

07

D

C07D 311/58 (2006.01) A61K 31/35 (2006.01) A61K 31/352 (2006.01) A61K 31/381 (2006.01) A61K 31/382 (2006.01) A61K 31/4184 (2006.01) A61K 31/4433 (2006.01) A61K 31/453 (2006.01) A61K 31/47 (2006.01) A61K 31/5377 (2006.01) A61P 19/02 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01) C07D 215/54 (2006.01) C07D 221/00 (2006.01) C07D 307/00 (2006.01) C07D 311/00 (2006.01) C07D 311/12 (2006.01) C07D 311/38 (2006.01) C07D 311/92 (2006.01) C07D 317/00 (2006.01) C07D 335/06 (2006.01) C07D 405/

Patent

CA 2347910

A class of benzopyrans, benzothiopyrans, dihydroquinolines, dihydronaphthalenes, and analogs thereof, is described for use in treating cyclooxygenase-2 mediated disorders. Compounds of particular interest are defined by Formula (I') wherein X, A1, A2, A3, A4, R, R'', R1 and R2 are as described in the specification.

Classe de benzopyrannes, benzothiopyrannes, dihydroquinolines, dihydronaphtalènes, et analogues desdites substances, destinés à être utilisés pour traiter les troubles liés à la cyclooxygénase-2. Des composés particulièrement intéressants répondent à la formule (I') dans laquelle X, A?1¿, A?2¿, A?3¿, A?4¿, R, R'', R?1¿ et R?2¿ sont tels que définis dans le descriptif.

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