Substituted benzopyrans as selective estrogen receptor-beta...

C - Chemistry – Metallurgy – 07 – D

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C07D 311/60 (2006.01) A61P 35/00 (2006.01) C07D 311/80 (2006.01) C07D 311/94 (2006.01)

Patent

CA 2467013

The present invention relates to substituted benzopyran derivatives,stereoisomers, and pharmaceutical acceptable salts thereof and processes for the preparation of the same. The compounds of the present invention are useful as Estrogen Receptor .beta. agonists. Such agonists are useful for the treating Estrogen Receptor .beta. mediated diseases such as prostate cancer.

La présente invention concerne des dérivés benzopyrans substitués, leurs stéréoisomètres, et certains de leurs sels pharmaceutiquement admis. L'invention concerne également les procédés d'élaboration correspondants. Les composés de l'invention conviennent comme agonistes du récepteur aux oestrogènes .beta.. De tels agonistes conviennent pour le traitement d'affections à médiation du récepteur aux oestrogènes .beta. telles que le cancer de la prostate.

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