C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 333/68 (2006.01) A61K 31/16 (2006.01) A61K 31/33 (2006.01) A61P 11/06 (2006.01) A61P 19/02 (2006.01) A61P 29/00 (2006.01) C07C 233/63 (2006.01) C07C 235/54 (2006.01) C07C 235/84 (2006.01) C07C 311/15 (2006.01) C07C 317/14 (2006.01) C07C 323/62 (2006.01) C07D 333/78 (2006.01)
Patent
CA 2690001
The present invention relates to A compound of the formula Ia wherein in any of its stereoisomers forms or a mixture of stereoisomeric forms in any ratio, or a physiologically acceptable salt thereof, wherein the substituents are as described herein. The inventive compounds have CXCR5 inhibitory activity are particularly useful in treating or preventing various inflammatory diseases, such as rheumatoid arthritis, multiple sclerosis, lupus, Crohn's Disease, associated with the modulation of the human CXCR5 receptor.
La présente invention concerne un composé A de formule Ia sous l'une quelconque de ses formes stéréoisomères ou un mélange de formes stéréoisomères sous un rapport quelconque, ou un sel physiologiquement acceptable de celui-ci, les substituants étant tels que décrits ici. Les composés inventifs ont une activité inhibitrice de CXCR5 et sont particulièrement utiles pour traiter ou prévenir diverses maladies inflammatoires, telles que la polyarthrite rhumatoïde, la sclérose en plaques, le lupus, la maladie de Crohn, associées à la modulation du récepteur de CXCR5 humain.
Caulfield Thomas J.
Clemens Jennifer
Francis Robert S.
Freed Brian S.
John Stanly
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sanofi-Aventis
LandOfFree
Substituted benzoylamino-indan-2-carboxylic acids and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Substituted benzoylamino-indan-2-carboxylic acids and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted benzoylamino-indan-2-carboxylic acids and... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2007932