Substituted benzoylurea derivatives or their salts,...

Details Substituted benzoylurea derivatives or their salts,... Substituted benzoylurea derivatives or their salts,...

C - Chemistry, Metallurgy

07

D

C07D 239/34 (2006.01) A61K 31/505 (2006.01) A61K 31/535 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 413/12 (2006.01) C07F 9/547 (2006.01)

Patent

CA 2084428

ABSTRACT The present invention provides a substituted benzoylurea derivative having the formula (I), Image (I) (wherein Q is a -R1N(Z2)Z3 group or a -R2N(Z4)CORlN(Z2)Z3 group, R1 and R2 are respectively an alkanediyl group which may be substituted with a lower alkylthio group or a phenyl group, Z1, Z2' Z3 and Z4 are respectively a hydrogen atom or a lower alkyl group, Rl and Z2 may be bonded with each other to form a heterocyclic ring with an adjacent nitrogen atom, X is a halogen atom, a lower alkyl group or a CF3 group, and Y is a halogen atom) or its salt, effective as an antitumor agent; a method for producing the same; an antitumor composition containing the same; and an intermediate product for producing the same.

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