Substituted benzylamine derivatives and methods of use

Details Substituted benzylamine derivatives and methods of use Substituted benzylamine derivatives and methods of use

C - Chemistry, Metallurgy

07

D

C07D 213/81 (2006.01) A61K 31/44 (2006.01) A61K 31/4427 (2006.01) A61K 31/4545 (2006.01) A61P 35/00 (2006.01) C07D 213/82 (2006.01) C07D 237/04 (2006.01) C07D 237/24 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/12 (2006.01) C07D 407/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/12 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2492164

Selected compounds of formula IV are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as intermediates useful in such processes (IV).

des composés sélectionnés représentés par la formule IV sont efficaces pour la prophylaxie et le traitement de maladies telles que des maladie induites par l'angiogenèse. La présente invention concerne de nouveaux composés, analogues, promédicaments et des dérivés de ceux-ci qui répondent aux normes pharmaceutiques, des compositions pharmaceutiques et des procédés de prophylaxie et de traitement de maladies et d'autres maladies ou états impliquant un cancer ou une pathologie similaire. Cette invention concerne aussi des processus de fabrication de ces composés ainsi que des intermédiaires utiles dans ces processus (IV).

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