Substituted .beta.-diketones

Details Substituted .beta.-diketones Substituted .beta.-diketones

C - Chemistry, Metallurgy

07

C

167/179, 260/295

C07C 49/213 (2006.01) A61K 31/00 (2006.01) A61K 31/06 (2006.01) A61K 31/12 (2006.01) C07C 65/32 (2006.01) C07C 255/56 (2006.01)

Patent

CA 1338420

Image (Ia) Image (Ib) wherein R1 and R2 are each independently hydrogen, alkyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms, hydroxy, aryl or heteroaryl or amino, the alkyl, aryl, heteroaryl or amino group being optionally subtituted; R3 is hydrogen, optionally substituted alkyl of 1 to 6 carbon atoms or optionally substituted aryl or heteroaryl and salts, ethers and esters thereof are useful as cytoprotective agents, especially for the treatment or prophylaxis of ulcers, lesions or like condition in the gastrointestinal tract.

609963

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