Substituted bicyclic aryl compounds exhibiting selective...

C - Chemistry – Metallurgy – 07 – D

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C07D 209/24 (2006.01) A61K 31/195 (2006.01) A61K 31/405 (2006.01) A61K 31/435 (2006.01) C07C 235/34 (2006.01) C07C 235/78 (2006.01) C07D 209/12 (2006.01) C07D 209/42 (2006.01) C07D 213/56 (2006.01) C07D 215/14 (2006.01) C07D 295/185 (2006.01) C07D 307/81 (2006.01) C07D 333/60 (2006.01) C07D 403/02 (2006.01) C07D 403/06 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2091257

2091257 9204321 PCTABS00011 The invention relates to bicyclic aryl compounds having selective LTB4 antagonist properties and comprising an amido substituent , a substituent group having a terminal carboxylic acid or derivative thereof and a lipophilic substituent, and to methods for the treatment of disorders which result from LTB4 activity and pharmaceutical compositions including such compounds.

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