C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/64 (2006.01) A61K 31/435 (2006.01) A61K 31/505 (2006.01) A61K 31/55 (2006.01) C07C 39/15 (2006.01) C07C 43/205 (2006.01) C07C 57/42 (2006.01) C07C 59/68 (2006.01) C07C 69/712 (2006.01) C07D 213/70 (2006.01) C07D 215/14 (2006.01) C07D 215/227 (2006.01) C07D 215/36 (2006.01) C07D 215/38 (2006.01) C07D 239/32 (2006.01) C07D 239/34 (2006.01) C07D 239/38 (2006.01) C07D 239/78 (2006.01) C07D 239/80 (2006.01) C07D 401/02 (2006.01) C07D 401/12 (2006.01) C07D 405/00 (2006.01) C07D 405/04 (2006.01) C07D 405/
Patent
CA 2087848
2087848 9201675 PCTABS00010 This invention relates to compounds having selective LTB4 antagonist properties and comprising an aryl or heteroaryl mono- or bicyclic ring which has at least two substituents attached thereto; (1) a substituted or unsubstituted aryl or heteroaryl mono- or bicyclic ring and (2) a substituent chain having a terminal carboxylic acid functional group or derivative thereof attached thereto. This invention further relates to processes for their preparation and therapeutic compositions comprising said compound and methods for the treatment of disorders involving LTB4 agonist-mediated activity utilizing said compositions wherein the compounds are described by general formula (I) and pharmaceutically acceptable salts thereof.
Dereu Norbert
Hendel Wolfram
Labaudiniere Richard
Dereu Norbert
Hendel Wolfram
Labaudiniere Richard
Rhone-Poulenc Rorer S.a.
Robic
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