Substituted bicyclic heterocycles, process for their...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 265/36 (2006.01) A61K 31/538 (2006.01) A61K 31/5415 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) C07D 279/16 (2006.01) C07D 413/06 (2006.01) C07D 413/12 (2006.01) C07D 417/06 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2371757

The present invention relates to novel antiobesity and hypocholesterolemic compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. More particularly, the present invention relates to novel .beta.-aryl-.alpha.-oxysubstituted alkylcarboxylic acids of general formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them.

Cette invention se rapporte à de nouveaux composés contre l'obésité et hypocholestérolémiques, à leurs dérivés, à leurs analogues, à leurs formes tautomères, à leurs stéréo-isomères, à leurs polymorphes, à leurs sels acceptables sur le plan pharmaceutique, à leurs solvates acceptables sur le plan pharmaceutique et à des compositions acceptables sur le plan pharmaceutique, contenant ces composés. Cette invention se rapporte plus particulièrement à de nouveaux acides alkylcarboxyliques .beta.-aryl-.alpha.-oxysubstitués, représentés par la formule générale (I), à leurs dérivés, à leurs analogues, à leurs formes tautomères, à leurs stéréo-isomères, à leurs polymorphes, à leurs sels acceptables sur le plan pharmaceutiques, à leurs solvates acceptables sur le plan pharmaceutiques et à des compositions acceptables sur le plan pharmaceutique, contenant ces acides.

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