Substituted bis-amide metalloprotease inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 239/28 (2006.01) A61K 31/506 (2006.01) A61P 19/00 (2006.01) C07D 403/12 (2006.01) C07D 409/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2635580

This invention relates to substituted bis-amide pyrimidine compounds of Formula (I), which are useful for the treatment of metalloprotease mediated diseases, in particular MMP-13 related diseases.

La présente invention concerne des composés de bis-amidopyrimidine substitués de formule (I), qui sont utiles pour le traitement de maladies à médiation par une métalloprotéase, en particulier les maladies liées à la MMP-13.

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