Substituted bisindolylmaleimides for the inhibition of cell...

C - Chemistry – Metallurgy – 07 – D

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C07D 403/14 (2006.01) A61K 31/404 (2006.01) A61K 31/454 (2006.01) A61P 35/00 (2006.01) C07F 9/6558 (2006.01)

Patent

CA 2392902

Disclosed are novel substituted pyrroles having formula (I). These compounds and their pharmaceutically acceptable salts are suitable for administration to patients as continuous infusion solution and are useful in the treatment and/or control of cell proliferative disorders, in particular cancer. Also disclosed are pharmaceutical compositions containing the foregoing compounds and methods for the treatment and/or control of cancer.

L'invention concerne des pyrroles substitués de formule (I). Ces composés et leurs sels pharmaceutiquement acceptables peuvent être administrés à des patients en tant que solution de perfusion continue, et servent au traitement et/ou au contrôle de troubles de prolifération cellulaire, en particulier du cancer. L'invention concerne également des compositions pharmaceutiques contenant lesdits composés, et des procédés de traitement et/ou de contrôle du cancer.

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