Substituted bridged-diazabicycloalkyl quinolone carboxylic...

Details Substituted bridged-diazabicycloalkyl quinolone carboxylic... Substituted bridged-diazabicycloalkyl quinolone carboxylic...

C - Chemistry, Metallurgy

07

D

167/180, 260/273

C07D 471/08 (2006.01) A61K 31/435 (2006.01) A61K 31/55 (2006.01) C07D 487/08 (2006.01) C07D 519/00 (2006.01)

Patent

CA 1340734

Antibacterial compounds have the formula (see formula I) wherein R1 is hydrogen, a pharmaceutically acceptable cation, or alkyl; A is CH, CF, CCl or N; Y is alkyl, haloalkyl, cyclopropyl, vinyl, methoxy, N-methylamino, p-fluorophenyl, p-hydroxyphenyl or p-aminophenyl; or A is carbon and is taken together with Y and the carbon and nitrogen to which A and Y are attached to form a five to seven membered ring which is optionally substituted; and R2 is a bridged-diazabicycloalkyl group.

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