C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 237/28 (2006.01) A61K 31/497 (2006.01) A61K 31/502 (2006.01) A61K 31/506 (2006.01) A61P 25/22 (2006.01) A61P 25/24 (2006.01) A61P 25/28 (2006.01) C07D 401/10 (2006.01) C07D 403/10 (2006.01)
Patent
CA 2634305
This invention relates to novel Cinnoline -based compounds and their pharmaceutically acceptable salts, tautomers or in vivo- hydrolysable precursors, compositions and methods of use thereof. These novel compounds provide a treatment or prophylaxis of dementia due to Parkinson's disease, dementia due to Alzheimer's disease as well as anxiety disorders, cognitive disorders, and/or mood disorders.
La présente invention concerne des composés innovants à base de cinnoline et leurs sels pharmaceutiquement acceptables, des tautomères ou des précurseurs hydrolysables in vivo, des compositions et des procédés d'utilisation. Ces composés innovants sont destinés au traitement ou à la prophylaxie de la démence causée par la maladie de Parkinson ou par la maladie d'Alzheimer ainsi que de l'anxiété, des troubles cognitifs et/ou du dérèglement de l'humeur.
Becker Christopher
Chang Hui-Fang
Chapdelaine Marc
Dembofsky Bruce
Ohnmacht Cyrus
Astrazeneca Ab
Mccarthy Tetrault Llp
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