Substituted cyclohexanols and cyclohexylamines as central...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/04 (2006.01) A61K 31/395 (2006.01) C07D 211/82 (2006.01) C07D 213/74 (2006.01) C07D 213/82 (2006.01) C07D 401/08 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/08 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2031588

Substituted cyclohexanols and cyclohexylamines and derivatives thereof are described, as well as methods for the preparation and pharmaceutical composition of same, which are useful as central nervous system agents and are particularly useful as dopaminergic, antiphyschotic, and antihypertensive agents as well as for treating hyperprolactinaemia- related conditions and central nervous system disorders. Compounds according to the invention have a structure of the following general formula: (see formula I)

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