C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) A61K 31/10 (2006.01) A61K 31/445 (2006.01) A61P 25/18 (2006.01) A61P 25/22 (2006.01) A61P 25/24 (2006.01) C07C 317/14 (2006.01) C07D 207/14 (2006.01) C07D 211/34 (2006.01) C07D 213/38 (2006.01) C07D 265/30 (2006.01) C07D 403/04 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01) C07D 471/04 (2006.01) C07D 471/10 (2006.01)
Patent
CA 2611867
The present invention relates to the compounds of formula (I): wherein A,B, n, X, Y, Z, R1, R2, R3, R4, R5, R6, R7 and R8 are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them and their use in treating diseases mediated by neurokinin-3 (NK-3) receptors. These compounds can thus be used in methods of treatment to suppress and treat such disorders.
La présente invention concerne des composés de la formule (I) : (A J- S(O)n-X^ V- Z-N (I) R2 où A5B, n, X, Y, Z, R1, R2, R3, R4, R5, R6, R7 et R8 sont définis ici, et des sels pharmaceutiquement acceptables de ceux-ci, des compositions pharmaceutiques les comprenant et leur utilisation dans le traitement de maladies à médiation par des récepteurs de la neurokinine 3 (NK-3). Ces composés peuvent alors être utilisés dans des procédés de traitement pour supprimer et traiter de tels troubles.
Dirat Olivier
Elliott Jason Matthew
Owens Andrew Pate
Shaw Duncan Edward
Sternfeld Francine
Merck Sharp & Dohme Limited
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
LandOfFree
Substituted cyclohexyl derivatives as nk-3 receptor antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Substituted cyclohexyl derivatives as nk-3 receptor antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted cyclohexyl derivatives as nk-3 receptor antagonists will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1451359