Substituted derivatives of diaminophthalimide

Details Substituted derivatives of diaminophthalimide Substituted derivatives of diaminophthalimide

C - Chemistry, Metallurgy

07

D

C07D 209/48 (2006.01) A61K 31/395 (2006.01) A61K 31/675 (2006.01) C07C 229/62 (2006.01) C07C 233/36 (2006.01) C07C 233/47 (2006.01) C07C 237/06 (2006.01) C07C 275/14 (2006.01) C07C 275/16 (2006.01) C07C 279/14 (2006.01) C07C 335/08 (2006.01) C07D 241/42 (2006.01) C07D 487/04 (2006.01) C07F 9/572 (2006.01)

Patent

CA 2109993

Abstract Substituted derivatives of diaminophthalimide There are described compounds of the formula I Image (I) in which A1 and A2 independently of one another are substituted lower alkyl, substituted lower alkenyl, substituted lower alkynyl or hydrogen, where maximally one of the radicals A1 and A2 can be hydrogen, or A1 and A2 together are lower alkylene substituted by substituents other than lower alkyl and other than hydroxyl; Ar1 and Ar2 independently of one another are aryl, heteroaryl or unsubstituted or substituted cycloalkyl, the group -C(=X)- is -C(=O)-, -C(=S)-, -CH2- or -C(=CR1R2)-, where R1 and R2 independently of one another are hydrogen or lower alkyl, and R is hydrogen, lower alkyl, aryl-lower alkyl, aryl, amino, hydroxyl or lower alkoxy, salts thereof if salt-forming groups are present, and/or tautomers thereof if tautomerizable radicals are present, processes for the preparation of these compounds, pharmaceutical preparations which contain these compounds, and the use of these compounds for the therapeutic treatment of the human or animal body or for the production of pharmaceutical preparations.

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