Substituted di- and tripeptide inhibitors of...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 5/097 (2006.01) A61K 38/05 (2006.01) A61K 38/06 (2006.01) C07K 5/078 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2170766

Novel inhibitors of protein:farnesyl transferase enzyme are described, as well as methods for the preparation and pharmaceutical compositions of the same, which are useful in controlling tissue proliferative diseases, including cancer and restenosis.

L'invention concerne de nouveaux inhibiteurs de l'enzyme protéine:farnésyle transférase, de même que des procédés de préparation de ceux-ci ainsi que des compositions pharmaceutiques contenant lesdits inhibiteurs, lesquels sont utiles dans la maîtrise des maladies à prolifération tissulaire, notamment le cancer et la resténose.

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