Substituted dihydroisoindolones as allosteric modulators of...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/12 (2006.01) A61K 31/465 (2006.01) A61P 3/10 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2627892

The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating glucokinase mediated disorders. More particularly, the compounds of the present invention are glucokinase modulators useful for treating disorders including, but not limited to, type II diabetes.

La présente invention concerne des composés de formule (I), des méthodes pour préparer lesdits composés, des compositions, des intermédiaires et des dérivés de ceux-ci, et pour traiter des troubles médiés par la glucokinase. Plus particulièrement, les composés de la présente invention sont des modulateurs de la glucokinase utiles pour traiter des troubles y compris, mais sans s'y limiter, le diabète de type II.

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