Substituted dihydroisoquinoline and phthalazine derivatives...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 217/24 (2006.01) A61K 31/47 (2006.01) A61K 31/50 (2006.01) A61K 31/535 (2006.01) C07D 237/32 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01)

Patent

CA 1334969

The invention is selected, novel, and known analogs of isoquinolines and phthalazines of the formula Image and pharmaceutically acceptable salts thereof; novel pharmaceutical compositions; and a method for enhancing the lethal effects for tumor cells to treatment having DNA damaging activity such as ionizing radiation or chemotherapeutic agents.

608774

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