Substituted dihydrophenanthridinesul fonamides

Details Substituted dihydrophenanthridinesul fonamides Substituted dihydrophenanthridinesul fonamides

C - Chemistry, Metallurgy

07

D

C07D 221/12 (2006.01) A61K 31/473 (2006.01) A61P 9/00 (2006.01) A61P 11/00 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) C07D 401/04 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01)

Patent

CA 2508329

This invention provides a compound of formulae (I) or (II) having the structure or a pharmaceutically acceptable salt thereof which are useful for the treatment of the inflammatory component of diseases and are particularly useful in treating atherosclerosis, myocardial infarction, congestive heart failure, inflammatory bowel disease, arthritis, type II diabetes, and autoimmune diseases such as multiple sclerosis and rheumatiod arthritis.

L'invention concerne un composé de formules (I) ou (II) ou un sel pharmaceutiquement acceptable de ce composé, qui sert à traiter la composante inflammatoire de maladies. Ce composé est particulièrement utilisé pour traiter l'athérosclérose, l'infarctus du myocarde, l'insuffisance cardiaque globale, la maladie intestinale inflammatoire, l'arthrite, le diabète de type II et des maladies auto-immunes telles que la sclérose en plaques et l'arthrite rhumatoïde.

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