C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/22 (2006.01) A61K 31/519 (2006.01) A61P 35/00 (2006.01) C07D 471/14 (2006.01)
Patent
CA 2756807
The present invention relates to substituted dipyrido-pyrimido-diazepine compounds of formula (I), substituted benzo-pyrido-pyrimido-diazepine compounds of formula (I) and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted dipyrido- pyrimido-diazepine compounds, substituted benzo--pyrido-pyrimido- diazepine compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds and pharmaceutical compositions to subjects in need thereof.
La présente invention porte sur des composés dipyrido-pyrimido-diazépine substitués de formule (I), sur des composés benzo-pyrido-pyrimido-diazépine substitués de formule (I) et sur des procédés de synthèse de ces composés. La présente invention porte également sur les compositions pharmaceutiques contenant des composés dipyrido-pyrimido-diazépine substitués, sur des composés benzo-pyrido-pyrimido- diazepine substitués et sur des procédés de traitement de troubles prolifératifs cellulaires, tels que le cancer, par l'administration de ces composés et de ces compositions pharmaceutiques à des sujets en ayant besoin.
Ashwell Mark A.
Liu Yanbin
Namdev Nivedita
Palma Rocio
Tandon Manish
Arqule Inc.
Ridout & Maybee Llp
LandOfFree
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