Substituted fused-ring compounds for inflammation and...

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 233/64 (2006.01) A61K 31/166 (2006.01) A61K 31/196 (2006.01) A61K 31/215 (2006.01) A61K 31/5375 (2006.01) C07C 233/75 (2006.01) C07C 233/81 (2006.01) C07D 265/32 (2006.01)

Patent

CA 2678615

The invention relates to compounds of structural formula (I) or (II): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof, wherein L, L1, Y, R1, R2, R9, Ri10, ring A, ring B, ring C, and ring D are defined herein. These compounds are useful as immunosuppressive agents and for treating and preventing inflammatory conditions, allergic disorders, and immune disorders.

L'invention concerne des composés de la formule structurelle (I) ou (II) : ou un sel, solvat, clathrate ou promédicament pharmaceutiquement acceptable de ceux-ci, où L, L1, Y, R1, R2, R9, R10, le cycle A, le cycle B, le cycle C et le cycle D sont définis ici. Ces composés sont utiles comme agents immunosuppresseurs ainsi que pour traiter et éviter des infections inflammatoires, des troubles allergiques et des troubles immunitaires.

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